Domestic Shipping: At the moment, merchandise will be shipped solely inside the U.S. However when I, and you I am positive, get a chilly sore, I want to get rid of it as shortly and painlessly as possible. The exception to the rule is the DOT1 family, members of which methylate K79 within the globular region of histone H3 and which are structurally not associated to SET-area proteins 4 - 6 Recent work means that SET-domain-containing proteins methylate a number of proteins in addition to histones (see later)